• Rai stage 0: Lymphocytosis without enlargement of the lymph nodes, liver or spleen, and absence of anemia and thrombocytopenia.
  • Rai stage I: Lymphocytosis with enlargement of lymph nodes but without enlargement of the liver or spleen, anemia, or thrombocytopenia.
  • Rai stage II: Lymphocytosis with or without enlargement of lymph nodes but with enlargement of liver or spleen enlargement.
  • Rai stage III: Lymphocytosis and anemia (hemoglobin < 11g/dL) with or without enlargement of lymph nodes, liver, and spleen.
  • Rai stage IV: Lymphocytosis and thrombocytopenia (<100,000/mm3 ) with or without enlargement of lymph nodes, liver, and spleen.