Hormones exist naturally in the body. Estrogen and progesterone can stimulate cell growth in the mucosa of the uterus. You specialist may suggest hormone therapy if you have advanced or recurring uterine cancer.

The main treatment given is progesterone. This can help lower the size of the tumor and control symptoms. It is normally taken in tablet form, though it may sometimes be given parenterally (injection). The most common drugs given are:

  • medroxyprogesterone acetate
  • megestrol

The main side effects of progesterone are:

  • increased appetite
  • weight gain
  • fluid build-up (for example, swollen ankles)
  • nausea

The side effects may be mild, and it is unusual to have all of them. If you notice you have any side effects, tell your doctor.